I found this article at Curds & Whey website and thought I would post it for your consideration.
I have been asked quite often why I do not stock annatto colouring. The following article illustrates why.
Annatto orange-yellow colour is a vegetable dye made from the
seed coat of the tropical Annatto tree (bixa orellana). In Australia it is commonly used in cereals, snack foods, dairy foods including yoghurts, icecreams and cheeses, snack foods and a wide range of other foods.
It is the only natural colour that has so far been found to cause as many adverse intolerance reactions as artificial colours and to affect more consumers than artificial colours. It has also been associated with rare allergic reactions. Adverse reactions to annatto can include skin, gastrointestinal, airways and central nervous system reactions.