Coagulation of milk is an essential step in the production of most varieties of cheese. To achieve high quality and high performance cheese, coagulant activity should be limited to the hydrolysis of kappa casein. The activity proteolytic broad spectrum can cause serious defects in the quality of cheese flavors including bitter and weak body. The more specific enzyme known for the purpose of coagulating milk is chymosin. Coagulator , being a calf rennet, the standard sets a guaranteed high content of chymosin 92% of the active component.